广西中医药大学第一附属医院男科团队历经20年研究发现，中药验方强精煎可有效提高男性生育能力。
After 20 years of research, the andrology department team of the first affiliated hospital of Guangxi University of traditional Chinese Medicine found that Qiangjing decoction of traditiona Chinese medicine can effectively improve male fertility.
男性不育症是男科常见疾病，根据WHO统计，全世界约有15%的育龄夫妇遭受不育的困扰，男方因素约占50%。
Male infertility is a common disease inandrology. According to the statistics of WHO, about 15% of couples ofchildbearing age in the world suffer from infertility, and the male factoraccounts for about 50%.
随着社会的迅速发展，环境污染加剧，工作压力增加，生活习惯的改变，男性生育能力正逐年下降，在过去20年间，全球男性精子浓度以平均每年2.6%速度下降，正常精子比例和活力平均每年分别下降0.7%和0.3%。
With the rapid development of thesociety, the aggravation of environmental pollution, the increase of workpressure and the change of life styles，male fertility isdecreasing year by year. In the past 20 years, the global male spermconcentration has decreased at an average rate of 2.6% per year, while theproportion of normal sperm and vitality have decreased by 0.7% and 0.3% peryear respectively.
由于病因复杂，发病机制不明确，目前对男性不育症的治疗上仍缺乏针对性的药物，临床上依然采用经验用药为主。
Due to the complex etiology and unclearpathogenesis, there is still a lack of targeted drugs in the treatment of maleinfertility, and empirical drugs are still mainly used in clinical practice。
中医药治疗男性不育症有独特疗效，传统中医理论认为“肾藏精，主生殖”，肾精的盛衰直接决定人体的生殖机能，肾精充盛促使“天癸”成熟，在男子则表现为“精气溢泻”，肾精亏虚是男性不育症的主要原因。
Traditional Chinese medicine has aunique effect on male infertility. According to the TCM theory, "The肾（shen zang:Including but not limited to the kidneys.） stores essence, andgoverns reproduction. " it rise and fall for the essence of the肾（shen）decides the reproductivefunction of human body directly, the essence of the肾（shen） essence enrichingpromotes maturity of "Tiangui" , in the man is shown as "overflow of jing and qi(精气溢泻jing qi yi xie)", the essence of the肾（shen） deficiency is the mainreason of male infertility.
广西名中医宾彬教授根据传统中医理论，结合现代社会生活环境的变迁，提出男性不育患者的中医病因病机为以脾肾两虚为本，以湿热瘀阻为标，治疗原则为：以健脾补肾为主，兼以化湿活血为辅，并据此创立验方 强精煎 。
Combining the TCM theory with modernsocial changes, Professor Binbin suggested that, male infertility take deficiency of the 脾（pi zang:Including but not limited to the spleen）and the 肾（shen） as original cause andhot-humid and blood stasis is the superficial cause，and the therapeuticprinciple is mainly based oninvigorating 脾（pi） and 肾（shen）(健脾补肾jian pi bu shen)，and partially based on dispelling dampness and activating blood(化湿活血hua shi huo xue).According to this theory，Professor Binbin makes an effective recipe— Qiang Jing decoction .
强精煎 于临床应用20余年，为了更好地明确强精煎治疗男性不育症的作用机制，广中医男科团队在宾彬教授的带领下对强精煎展开长达十余年的深入研究，以强精煎为研究主体获得两项国家自然科学基金项目支持，发表相关论文20余篇。
Qiangjing decoction has been used inclinical practice for more than 20 years，many infertilitypatients cured by its reliable effect. In order to better demonstrate themechanisms of Qiangjing decoction in curing male infertility ，the andrology team fromfirst affiliated hospital of Guangxi university of TCM, under the leadership ofprofessor Binbin, carried out in-depth researchers of Qiangjing decoction formore than 10years, and supported by two NSFC projects，published scores ofpapers in journals.
临床研究表明， 强精煎 可有效提高精子数量、活力，改善精子形态，促进精液液化，以及提高精子顶体酶功能，且服药期间无明显不良反应。
Clinical studies have shown that QiangJing decoction can effectively improve sperm count and motility，reduce sperm abnormalrate， promote semen liquefaction， and improve spermacrosomal enzyme function, and there is no obvious adverse reaction during drugadministration.
强精煎 可改善少弱精子症模型大鼠的附睾和*丸睾**的超微结构，修复大鼠生精上皮，促进精原细胞的分化，调控精子发生，改善生精障碍，增强受精能力。
Animal experimental studies have shownthat Qiang Jing decoction canimprove the ultrastructure of epididymis and testis, repair the spermatogenicepithelium, promote the differentiation of spermatogenic cells, regulatespermatogenesis, improve the spermatogenic disorder and enhance the ability offertilization in oligoasthenospermia model rats.
Mechanism of Qiang Jing decoction in thetreatment of male infertility are：
1.抑制氧化应激反应，增强氧化酶活性，改善能量代谢
1.Inhibit oxidative stress,enhance oxidase activity, and improve energy metabolism
2.下调少弱精子症模型大鼠附睾精子PDE基因表达水平并显著上调其AC基因表达水平
2.Down-regulated theexpression level of PDE gene and up-regulated the expression level of AC genesignificantly in epididymal sperm of oligoasthenospermia model rats.
3.提高*丸睾**和附睾Na + － K + －ATPase 和Ca2 + － ATPase 活性
3.Improving activity of Na + - K + -ATPase and Ca2 + -ATPase intesticular and epididymal
4.上调了c － kit and CFTＲ蛋白表达
4.Up-regulated the expression of c-kit and CFTR
5.抑制Bax、Fas 和Fasl，并促进Bcl-2蛋白在受损伤小鼠*丸睾**实质组织中的表达
5.It inhibited the expression of Bax、 Fas and Fasl, and promoted the expression of bcl-2 protein in the testicular.
研究表明，补肾健脾为主的中药可有效提高男性生育能力。
The researchfound that Qiangjing decoction of traditiona Chinese medicine can effectively improve male fertility.