作者：Ghada M Mansour, et al.
译者：郭乾育
译者简介: 女，1978年生，硕士，山西大医院风湿免疫科副主任医师。山西省医师协会风湿免疫专业委员会委员，中国医师协会免疫吸附学术委员会山西分会委员，北大医学部国内访问学者。2007年毕业于山西医科大学获硕士学位，2014年经山西省卫计委遴选作为国内访问学者派至北京大学医学部进行学习及研修1年。
发表文章15篇，其中第一作者发表中华级文章2篇，SCI论文1篇，影响因子2.653，主编《风湿免疫科住院医师问答》1部，副主编《风湿免疫科主治医师836问》1部。从事风湿性疾病临床工作17年，主要研究方向是晶体性关节炎的诊治、类风湿关节炎早期诊断及治疗。
擅长痛风、类风湿关节炎、脊柱关节炎等炎性关节炎的诊治，对常见结缔组织病如系统性红斑狼疮、干燥综合征、系统性硬化病、系统性血管炎等也有较丰富的临床经验。
【摘要】
目的：观察复发性妊娠丢失患者子宫动脉血流及波形变化，并与正常对照组进行比较。
研究对象和方法：采用经阴道多普勒超声对50名正常对照妇女及50例两次或两次以上连续妊娠丢失病史的妇女进行检查，评估在黄体中期子宫内膜血流阻力指数、子宫动脉多普勒波形分型及子宫动脉搏动指数。
结果：复发性妊娠丢失组患者子宫内膜下血流阻力（RI）、子宫动脉搏动指数（PI）均高于健康对照组，波形以A型或舒张流量减少为主，而对照组则以C型为主。结论：反复妊娠丢失患者可表现为子宫内膜和子宫内膜下缺血，给予子宫内膜血管增强剂治疗后，可根据子宫动脉波形模式的变化来评估子宫动脉血流的变化。
附原文
Purpose: To assess the sub endometrial and uterine artery blood flow and pattern of waveform of uterine artery in cases of recurrent pregnancy loss,compared to normal controls.Subjects and methods: Fifty women with a history of two or more successive pregnancy losses were investigated by Doppler transvaginal ultrasound to assess the sub endometrial blood flow resistance index, type of Doppler waveform of uterine artery, and uterine artery pulsatility index in the midluteal phase. Fifty normal women acted as controls.Results: Sub endometrial blood flow RI and uterine artery PI were higher in cases than controls. The majority of cases of recurrent pregnancy loss had a waveform pattern of A, or loss of diastolic flow, while the controls were mainly C wave. Conclusion:Some sort of endometrial and sub endometrial ischemia can
be suggested in cases of recurrent pregnancy loss, waveform pattern ofuterine artery changes may be used to monitor changes invascualrity of
endometrium if vascular enhancers are given in such cases.
Key words: Uterine artery waveform type, recurrent pregnancy loss, uterine artery pulsatility index (PI), sub endometrial blood flow resistance index (RI).
引自
Ghada M Mansour*, Sherif H. Hussein*,Rasha M. Abd Elhady*,Haitham F. Mohammed,MagdyM.Abd EL Gawad*, Ahmed I AbouGabal*, Rania M,Uterine Artery Flow velocity Waveform (FVW) Type andSubednometrial Vascularity In Recurrent Pregnancy Loss，The Journal of Maternal-Fetal & Neonatal Medicine,2018.