中文名

两性霉素 B

中文同义

两性霉素 B 三水合物;水溶两性霉素 B;两性霉素B(标准品);两性霉素B 来源于链霉菌 属;两性霉素 B 溶液;可溶性两性霉素;庐山霉素;多烯抗生素

英文名

Amphotericin B

英文同义

FUNGIZONE;FUNGIZONE(R);ABELCET;AMBISOME;AMPHOTERCIN B;AMPHOTERICIN B;AMPHOTERICIN B SOLUBILIZED;AMPHOTERICIN B, SOLUBLE

CAS

1397-89-3

分子式

C47H73NO17

分子量

924.08

EINECS

215-742-2

相关类别

医用原料;微生物代谢物;科研试剂;对照品,标准品;生化试剂;酶类;抗生素、生物碱;基因组学和分子诊断;各种化学试剂;小分子*制剂抑**;抗生素;Miscellaneous Natural Products;Antibiotic Explorer;AM to AQAntibiotics;MLS;A;Alphabetic;Chemical Structure;Antibiotics A to;Antibiotics A-FAntibiotics;AntibioticsAntibiotics;Inhibitors;小分子*制剂抑**，天然产物;抗生素类;医用原料;原料药;医药化工类;化学试剂;原料药API;医药原料;原料;合成抗菌药;化学试剂;Intermediates & Fine Chemicals;Pharmaceuticals;AntifungalAntibiotics;Cell Culture;Chemical Structure Class;Interferes with Cell Membrane Permeability (Ionophores)Antibiotics;Mechanism of Action;Polyenes;Reagents and Supplements;Spectrum of Activity;Antifungal;Carbohydrates & Derivatives;Chiral Reagents;ABELCET;antibiotic;APIs

结构式

性质

熔点

>170°C

比旋光度

D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)

沸点

804.34°C (rough estimate)

密度

1.34

折射率

1.5280 (estimate)

储存条件

2-8°C

溶解度

sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20?#x00b0;C. Stable at 37?#x00b0;C for 3 days.

酸度系数(pKa)

pKa ～5.7(DMF/H2O) (Uncertain)

形态

powder

颜色

yellow

水溶解性

<0.1 g/100 mL at 21 ºC

敏感性

Moisture & Light Sensitive

Merck

13,590

BRN

78342

稳定性

Stable, but may be light sensitive. Incompatible with strong oxidizing agents.

InChIKey

APKFDSVGJQXUKY-INPOYWNPSA-N

EPA化学物质信息

Amphotericin B (1397-89-3)